The Science of CALR: From Mutation Discovery to Emerging Therapeutic Strategies

MPN United Webinar Series – June 3, 2026

This session explores the scientific journey of CALR mutations, from initial discovery in the laboratory to their role in informing emerging therapeutic strategies. Using CALR as a case study, the webinar highlights how advances in genetic research translate into potential treatment approaches and future directions in MPN care.

Key Learning Objectives:

• Understand the process of mutation discovery in the laboratory, using CALR as a case study
• Explore the translational steps from genetic findings to therapeutic targets, including preclinical research and validation
• Understand how CALR discoveries progress through the early stages of therapeutic development
• Examine how scientific discoveries in CALR mutations inform the development of future therapeutic approaches
• Gain insights into emerging scientific directions and therapeutic strategies inspired by CALR-focused research

Speaker:
Dr. Robert Kralovics

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