Presented at the 24th Congress of the European Hematology Association (EHA), Promedior, Inc. announced today that positive safety and early efficacy clinical data was proven during their Phase 2 study of PRM-151 in myelofibrosis (MF) patients who were ineligible for Ruxolitinib or had failed the drug. Promedior looks forward to advancing the clinical program for PRM-151 in both MF and will explore other fibrotic indications in the future.
PRM-151 demonstrated promising antifibrotic activity as measured by a reduction in bone marrow fibrosis and improvement in hematologic measures. According to Dr. Srdan Verstovsek, Professor, Leukemia Department, MD Anderson Cancer Center. “Patients also showed a reduction in their myeloproliferative neoplasm symptoms, as well as a trend to prolonged survival with PRM-151 monotherapy in these refractory MF patients with great unmet need.”